A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma

Multiple myeloma (MM) is a heterogeneous haematological disease that remains clinically challenging. Increased activity of the epigenetic silencer EZH2 is a common feature in patients with poor prognosis. Previous findings have demonstrated that metabolic profiles can be sensitive markers for respon...

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Detalles Bibliográficos
Autores principales: Nylund, Patrick, Atienza Párraga, Alba, Haglöf, Jakob, De Bruyne, Elke, Menu, Eline, Garrido-Zabala, Berta, Ma, Anqi, Jin, Jian, Öberg, Fredrik, Vanderkerken, Karin, Kalushkova, Antonia, Jernberg-Wiklund, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881125/
https://www.ncbi.nlm.nih.gov/pubmed/33579905
http://dx.doi.org/10.1038/s41419-021-03447-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881125/
https://www.ncbi.nlm.nih.gov/pubmed/33579905
http://dx.doi.org/10.1038/s41419-021-03447-8

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