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Pd-catalyzed formal Mizoroki–Heck coupling of unactivated alkyl chlorides

The use of alkyl chlorides in Pd-catalyzed Mizoroki–Heck coupling reactions remains an unsolved problem despite their significant potential for synthetic utility and applicability. The combination of the high thermodynamic barrier of alkyl chloride activation and kinetic propensity of alkylpalladium...

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Detalles Bibliográficos
Autores principales: Lee, Geun Seok, Kim, Daeun, Hong, Soon Hyeok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881129/
https://www.ncbi.nlm.nih.gov/pubmed/33579940
http://dx.doi.org/10.1038/s41467-021-21270-9