Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor

The prognosis of recurrent malignant peripheral nerve sheath tumors (MPNST) is dismal, with surgical resection being the only definitive salvage therapy. Treatment with chemoradiation approaches has not significantly improved patient outcomes. Similarly, trials of therapies targeting MPNST genomic d...

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Detalles Bibliográficos
Autores principales: Nagabushan, Sumanth, Lau, Loretta M. S., Barahona, Paulette, Wong, Marie, Sherstyuk, Alexandra, Marshall, Glenn M., Tyrrell, Vanessa, Wegner, Eva A., Ekert, Paul G., Cowley, Mark J., Mayoh, Chelsea, Trahair, Toby N., Crowe, Philip, Anazodo, Antoinette, Ziegler, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881142/
https://www.ncbi.nlm.nih.gov/pubmed/33580196
http://dx.doi.org/10.1038/s41698-021-00145-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881142/
https://www.ncbi.nlm.nih.gov/pubmed/33580196
http://dx.doi.org/10.1038/s41698-021-00145-8

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