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miR-18a promotes glioblastoma development by down-regulating ALOXE3-mediated ferroptotic and anti-migration activities

The development of glioblastoma (GBM) is typically accompanied by marked changes in lipid metabolism. Oxylipins and their catalyzed enzymes lipoxygenases (LOXs) have been shown to participate in the development of cancers via multiple pathways, while the understanding of LOXs in GBM remains enigmati...

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Detalles Bibliográficos
Autores principales: Yang, Xinzhi, Liu, Jiangang, Wang, Chenci, Cheng, Kenneth King-yip, Xu, Hongchao, Li, Qingzhong, Hua, Tian, Jiang, Xue, Sheng, Lili, Mao, Jie, Liu, Zhuohao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881152/
https://www.ncbi.nlm.nih.gov/pubmed/33579899
http://dx.doi.org/10.1038/s41389-021-00304-3