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Molecular and phenotypic analysis of rodent models reveals conserved and species-specific modulators of human sarcopenia

Sarcopenia, the age-related loss of skeletal muscle mass and function, affects 5–13% of individuals aged over 60 years. While rodents are widely-used model organisms, which aspects of sarcopenia are recapitulated in different animal models is unknown. Here we generated a time series of phenotypic me...

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Detalles Bibliográficos
Autores principales: Börsch, Anastasiya, Ham, Daniel J., Mittal, Nitish, Tintignac, Lionel A., Migliavacca, Eugenia, Feige, Jérôme N., Rüegg, Markus A., Zavolan, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881157/
https://www.ncbi.nlm.nih.gov/pubmed/33580198
http://dx.doi.org/10.1038/s42003-021-01723-z