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C. elegans germ granules require both assembly and localized regulators for mRNA repression

Cytoplasmic RNA–protein (RNP) granules have diverse biophysical properties, from liquid to solid, and play enigmatic roles in RNA metabolism. Nematode P granules are paradigmatic liquid droplet granules and central to germ cell development. Here we analyze a key P granule scaffolding protein, PGL-1,...

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Detalles Bibliográficos
Autores principales: Aoki, Scott Takeo, Lynch, Tina R., Crittenden, Sarah L., Bingman, Craig A., Wickens, Marvin, Kimble, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881195/
https://www.ncbi.nlm.nih.gov/pubmed/33579952
http://dx.doi.org/10.1038/s41467-021-21278-1