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Down-regulation of habenular calcium-dependent secretion activator 2 induces despair-like behavior

Calcium-dependent secretion activator 2 (CAPS2) regulates the trafficking and exocytosis of neuropeptide-containing dense-core vesicles (DCVs). CAPS2 is prominently expressed in the medial habenula (MHb), which is related to depressive behavior; however, how MHb neurons cause depressive symptoms and...

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Detalles Bibliográficos
Autores principales: Yoo, Hyeijung, Yang, Soo Hyun, Kim, Jin Yong, Yang, Esther, Park, Hyung Sun, Lee, Se Jeong, Rhyu, Im Joo, Turecki, Gustavo, Lee, Hyun Woo, Kim, Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881199/
https://www.ncbi.nlm.nih.gov/pubmed/33580180
http://dx.doi.org/10.1038/s41598-021-83310-0