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A small-molecular inhibitor against Proteus mirabilis urease to treat catheter-associated urinary tract infections
Infection and blockage of indwelling urinary catheters is significant owing to its high incidence rate and severe medical consequences. Bacterial enzymes are employed as targets for small molecular intervention in human bacterial infections. Urease is a metalloenzyme known to play a crucial role in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881204/ https://www.ncbi.nlm.nih.gov/pubmed/33580163 http://dx.doi.org/10.1038/s41598-021-83257-2 |