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A small-molecular inhibitor against Proteus mirabilis urease to treat catheter-associated urinary tract infections

Infection and blockage of indwelling urinary catheters is significant owing to its high incidence rate and severe medical consequences. Bacterial enzymes are employed as targets for small molecular intervention in human bacterial infections. Urease is a metalloenzyme known to play a crucial role in...

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Detalles Bibliográficos
Autores principales: Milo, Scarlet, Heylen, Rachel A., Glancy, John, Williams, George T., Patenall, Bethany L., Hathaway, Hollie J., Thet, Naing T., Allinson, Sarah L., Laabei, Maisem, Jenkins, A. Toby A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881204/
https://www.ncbi.nlm.nih.gov/pubmed/33580163
http://dx.doi.org/10.1038/s41598-021-83257-2