Dissecting the impact of target-binding kinetics of protein binders on tumor localization

Systematic control of in vivo behavior of protein-based therapeutics is considered highly desirable for improving their clinical outcomes. Modulation of biochemical properties including molecular weight, surface charge, and binding affinity has thus been suggested to enhance their therapeutic effect...

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Detalles Bibliográficos
Autores principales: Song, Yunjin, Jeong, Hoibin, Kim, Song-Rae, Ryu, Yiseul, Baek, Jonghwi, Kwon, Jinhak, Cho, Hyeongjun, Kim, Kil-Nam, Lee, Joong-jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881221/
https://www.ncbi.nlm.nih.gov/pubmed/33615202
http://dx.doi.org/10.1016/j.isci.2021.102104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881221/
https://www.ncbi.nlm.nih.gov/pubmed/33615202
http://dx.doi.org/10.1016/j.isci.2021.102104

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