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The IL-27 receptor regulates TIGIT on memory CD4(+) T cells during sepsis
Sepsis is a leading cause of morbidity and mortality associated with significant impairment in memory T cells. These changes include the upregulation of co-inhibitory markers, a decrease in functionality, and an increase in apoptosis. Due to recent studies describing IL-27 regulation of TIGIT and PD...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881227/ https://www.ncbi.nlm.nih.gov/pubmed/33615199 http://dx.doi.org/10.1016/j.isci.2021.102093 |