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How μ-opioid receptor recognizes fentanyl

Roughly half of the drug overdose-related deaths in the United States are related to synthetic opioids represented by fentanyl which is a potent agonist of mu-opioid receptor (mOR). In recent years, X-ray crystal structures of mOR in complex with morphine derivatives have been determined; however, s...

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Detalles Bibliográficos
Autores principales: Vo, Quynh N., Mahinthichaichan, Paween, Shen, Jana, Ellis, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881245/
https://www.ncbi.nlm.nih.gov/pubmed/33579956
http://dx.doi.org/10.1038/s41467-021-21262-9