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Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes

Since the discovery of human induced pluripotent stem cells (hiPSCs), numerous strategies have been established to efficiently derive cardiomyocytes from hiPSCs (hiPSC-CMs). Here, we describe a cost-effective strategy for the subsequent massive expansion (>250-fold) of high-purity hiPSC-CMs relyi...

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Detalles Bibliográficos
Autores principales: Maas, Renee G.C., Lee, Soah, Harakalova, Magdalena, Snijders Blok, Christian J.B., Goodyer, William R., Hjortnaes, Jesper, Doevendans, Pieter A.F.M., Van Laake, Linda W., van der Velden, Jolanda, Asselbergs, Folkert W., Wu, Joseph C., Sluijter, Joost P.G., Wu, Sean M., Buikema, Jan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881265/
https://www.ncbi.nlm.nih.gov/pubmed/33615277
http://dx.doi.org/10.1016/j.xpro.2021.100334