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Prioritizing second-generation SARS-CoV-2 vaccines through low-dosage challenge studies

The design of human challenge studies balances scientific validity, efficiency and study safety. This Perspective explores some advantages and disadvantages of ‘low-dosage’ challenge studies, in the setting of testing second-generation vaccines against COVID-19. Compared with a conventional vaccine...

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Detalles Bibliográficos
Autores principales: Steuwer, Bastian, Jamrozik, Euzebiusz, Eyal, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881292/
https://www.ncbi.nlm.nih.gov/pubmed/33592338
http://dx.doi.org/10.1016/j.ijid.2021.02.038