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Enhanced anti-inflammatory effects of mesenchymal stromal cells mediated by the transient ectopic expression of CXCR4 and IL10

BACKGROUND: Mesenchymal stromal cells (MSCs) constitute one of the cell types most frequently used in cell therapy. Although several studies have shown the efficacy of these cells to modulate inflammation in different animal models, the results obtained in human clinical trials have been more modest...

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Detalles Bibliográficos
Autores principales: Hervás-Salcedo, Rosario, Fernández-García, María, Hernando-Rodríguez, Miriam, Quintana-Bustamante, Oscar, Segovia, Jose-Carlos, Alvarez-Silva, Marcio, García-Arranz, Mariano, Minguez, Pablo, del Pozo, Victoria, de Alba, Marta Rodríguez, García-Olmo, Damián, Ayuso, Carmen, Lamana, María Luisa, Bueren, Juan A., Yañez, Rosa María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881581/
https://www.ncbi.nlm.nih.gov/pubmed/33579367
http://dx.doi.org/10.1186/s13287-021-02193-0