Functional phenotyping of the CYP2D6 probe drug codeine in the horse

BACKGROUND: In humans, the drug metabolizing enzyme CYP2D6 is highly polymorphic resulting in substantial differences in the metabolism of drugs including anti-arrhythmics, neuroleptics, and opioids. The objective of this study was to phenotype a population of 100 horses from five different breeds a...

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Detalles Bibliográficos
Autores principales: Gretler, S. R., Finno, C. J., Kass, P. H., Knych, H. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881596/
https://www.ncbi.nlm.nih.gov/pubmed/33581736
http://dx.doi.org/10.1186/s12917-021-02788-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881596/
https://www.ncbi.nlm.nih.gov/pubmed/33581736
http://dx.doi.org/10.1186/s12917-021-02788-y

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