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Low-dose Diosbulbin-B (DB) activates tumor-intrinsic PD-L1/NLRP3 signaling pathway mediated pyroptotic cell death to increase cisplatin-sensitivity in gastric cancer (GC)

BACKGROUND: Emerging evidences suggests that Diosbulbin-B (DB) is effective to improve cisplatin (DDP)-sensitivity in gastric cancer (GC), but its molecular mechanisms were not fully delineated, and this study managed to investigate this issue. METHODS: Genes expressions were determined by Real-Time...

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Detalles Bibliográficos
Autores principales: Li, Chunfeng, Qiu, Junqiang, Xue, Yingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881658/
https://www.ncbi.nlm.nih.gov/pubmed/33579380
http://dx.doi.org/10.1186/s13578-021-00548-x