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Generation of inner ear sensory neurons using blastocyst complementation in a Neurog1(+/−)−deficient mouse
This research is the first to produce induced pluripotent stem cell-derived inner ear sensory neurons in the Neurog1(+/−) heterozygote mouse using blastocyst complementation. Additionally, this approach corrected non-sensory deficits associated with Neurog1 heterozygosity, indicating that complement...
Autores principales: | Steevens, Aleta R., Griesbach, Matthew W., You, Yun, Dutton, James R., Low, Walter C., Santi, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881691/ https://www.ncbi.nlm.nih.gov/pubmed/33579352 http://dx.doi.org/10.1186/s13287-021-02184-1 |
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