A Novel Allele-Specific PCR Protocol for the Detection of the HLA-C*03:02 Allele, a Pharmacogenetic Marker, in Vietnamese Kinh People

BACKGROUND: Allopurinol, a common anti-hyperuricemia drug, is well known as an inducer of severe cutaneous adverse drug reactions (SCARs). One of the most well-defined risk factors of allopurinol-induced SCARs is the presence of polymorphic alleles of human leukocyte antigen (HLA) genes, such as HLA...

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Detalles Bibliográficos
Autores principales: Pham, Tran Thu Ha, Tran, Quang Binh, Sukasem, Chonlaphat, Nguyen, Van Dinh, Chu, Chi Hieu, Do, Thi Quynh Nga, Tran, Ngoc Phuong Mai, Phung, Thanh Huong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881795/
https://www.ncbi.nlm.nih.gov/pubmed/33603436
http://dx.doi.org/10.2147/TACG.S278652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881795/
https://www.ncbi.nlm.nih.gov/pubmed/33603436
http://dx.doi.org/10.2147/TACG.S278652

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