A Polygenic Score for Type 2 Diabetes Risk Is Associated With Both the Acute and Sustained Response to Sulfonylureas

There is a limited understanding of how genetic loci associated with glycemic traits and type 2 diabetes (T2D) influence the response to antidiabetic medications. Polygenic scores provide increasing power to detect patterns of disease predisposition that might benefit from a targeted pharmacologic i...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Josephine H., Szczerbinski, Lukasz, Dawed, Adem Y., Kaur, Varinderpal, Todd, Jennifer N., Pearson, Ewan R., Florez, Jose C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881853/
https://www.ncbi.nlm.nih.gov/pubmed/33106254
http://dx.doi.org/10.2337/db20-0530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881853/
https://www.ncbi.nlm.nih.gov/pubmed/33106254
http://dx.doi.org/10.2337/db20-0530

Ejemplares similares