Glucagon Resistance and Decreased Susceptibility to Diabetes in a Model of Chronic Hyperglucagonemia

Elevation of glucagon levels and increase in α-cell mass are associated with states of hyperglycemia in diabetes. Our previous studies have highlighted the role of nutrient signaling via mTOR complex 1 (mTORC1) regulation that controls glucagon secretion and α-cell mass. In the current studies we in...

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Detalles Bibliográficos
Autores principales: Bozadjieva Kramer, Nadejda, Lubaczeuski, Camila, Blandino-Rosano, Manuel, Barker, Grant, Gittes, George K., Caicedo, Alejandro, Bernal-Mizrachi, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881862/
https://www.ncbi.nlm.nih.gov/pubmed/33239450
http://dx.doi.org/10.2337/db20-0440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881862/
https://www.ncbi.nlm.nih.gov/pubmed/33239450
http://dx.doi.org/10.2337/db20-0440

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