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SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients

The single nucleotide polymorphism rs7804356 located in the Src kinase-associated phosphoprotein 2 (SKAP2) gene is associated with type 1 diabetes (T1D), suggesting SKAP2 as a causal candidate gene. The objective of the study was to investigate if SKAP2 has a functional role in the β-cells in relati...

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Detalles Bibliográficos
Autores principales: Fløyel, Tina, Meyerovich, Kira, Prause, Michala C., Kaur, Simranjeet, Frørup, Caroline, Mortensen, Henrik B., Nielsen, Lotte B., Pociot, Flemming, Cardozo, Alessandra K., Størling, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881866/
https://www.ncbi.nlm.nih.gov/pubmed/33203694
http://dx.doi.org/10.2337/db20-0092