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SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients
The single nucleotide polymorphism rs7804356 located in the Src kinase-associated phosphoprotein 2 (SKAP2) gene is associated with type 1 diabetes (T1D), suggesting SKAP2 as a causal candidate gene. The objective of the study was to investigate if SKAP2 has a functional role in the β-cells in relati...
Autores principales: | Fløyel, Tina, Meyerovich, Kira, Prause, Michala C., Kaur, Simranjeet, Frørup, Caroline, Mortensen, Henrik B., Nielsen, Lotte B., Pociot, Flemming, Cardozo, Alessandra K., Størling, Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881866/ https://www.ncbi.nlm.nih.gov/pubmed/33203694 http://dx.doi.org/10.2337/db20-0092 |
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