The Dysregulated Galectin Network Activates NF-κB to Induce Disease Markers and Matrix Degeneration in 3D Pellet Cultures of Osteoarthritic Chondrocytes

This work aimed to study the dysregulated network of galectins in OA chondrocyte pellets, and to assess whether their recently discovered activity as molecular switches of functional biomarkers results in degradation of extracellular matrix in vitro. Scaffold-free 3D pellet cultures were established...

Descripción completa

Detalles Bibliográficos
Autores principales: Pichler, K. M., Weinmann, D., Schmidt, S., Kubista, B., Lass, R., Martelanz, L., Alphonsus, J., Windhager, R., Gabius, H. -J., Toegel, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881967/
https://www.ncbi.nlm.nih.gov/pubmed/33185768
http://dx.doi.org/10.1007/s00223-020-00774-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881967/
https://www.ncbi.nlm.nih.gov/pubmed/33185768
http://dx.doi.org/10.1007/s00223-020-00774-4

Ejemplares similares