A web tool for the design of prime-editing guide RNAs

Prime editing enables diverse genomic alterations to be written into target sites without requiring double-strand breaks or donor templates. The design of prime-editing guide RNAs (pegRNAs), which must be customized for each edit, can however be complex and time-consuming. Compared with single guide...

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Detalles Bibliográficos
Autores principales: Chow, Ryan D., Chen, Jennifer S., Shen, Johanna, Chen, Sidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882013/
https://www.ncbi.nlm.nih.gov/pubmed/32989284
http://dx.doi.org/10.1038/s41551-020-00622-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882013/
https://www.ncbi.nlm.nih.gov/pubmed/32989284
http://dx.doi.org/10.1038/s41551-020-00622-8

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