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A web tool for the design of prime-editing guide RNAs
Prime editing enables diverse genomic alterations to be written into target sites without requiring double-strand breaks or donor templates. The design of prime-editing guide RNAs (pegRNAs), which must be customized for each edit, can however be complex and time-consuming. Compared with single guide...
Autores principales: | Chow, Ryan D., Chen, Jennifer S., Shen, Johanna, Chen, Sidi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882013/ https://www.ncbi.nlm.nih.gov/pubmed/32989284 http://dx.doi.org/10.1038/s41551-020-00622-8 |
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