Effect of low dose IL-2 loaded chitosan nanoparticles on natural killer and regulatory T cell expression in experimentally induced autoimmune type 1 diabetes mellitus

INTRODUCTION: Natural killer cells (NK) initiate pancreatic islets cell lyses in autoimmune type 1 diabetes mellitus (T1D). Loss of T regulatory cells (Treg) at disease onset facilitates activation and accumulation of NKs in the pancreatic microenvironment. A proper low dose interleukin 2 (IL-2) cou...

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Detalles Bibliográficos
Autores principales: Aboelnazar, Salma, Ghoneim, Hossam, Shalaby, Thanaa, Bahgat, Eman, Moaaz, Mai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Experimental Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882410/
https://www.ncbi.nlm.nih.gov/pubmed/33658887
http://dx.doi.org/10.5114/ceji.2020.103412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882410/
https://www.ncbi.nlm.nih.gov/pubmed/33658887
http://dx.doi.org/10.5114/ceji.2020.103412

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