Cargando…

Effect of low dose IL-2 loaded chitosan nanoparticles on natural killer and regulatory T cell expression in experimentally induced autoimmune type 1 diabetes mellitus

INTRODUCTION: Natural killer cells (NK) initiate pancreatic islets cell lyses in autoimmune type 1 diabetes mellitus (T1D). Loss of T regulatory cells (Treg) at disease onset facilitates activation and accumulation of NKs in the pancreatic microenvironment. A proper low dose interleukin 2 (IL-2) cou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aboelnazar, Salma, Ghoneim, Hossam, Shalaby, Thanaa, Bahgat, Eman, Moaaz, Mai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2021
Materias:	Experimental Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882410/ https://www.ncbi.nlm.nih.gov/pubmed/33658887 http://dx.doi.org/10.5114/ceji.2020.103412

Ejemplares similares

Low-dose interleukin-2-loaded nanoparticle effect on NK and T-reg cell expression in experimentally induced type 1 diabetes mellitus
por: Aboelnazar, Salma, et al.
Publicado: (2021)

Association of hepatitis B vaccine response to vitamin D supplementation and ultraviolet B (UVB) exposure during different time intervals in experimental animals
por: Youssry, Sara, et al.
Publicado: (2022)

The powerful synergistic effect of spiramycin/propolis loaded chitosan/alginate nanoparticles on acute murine toxoplasmosis
por: Hagras, Nancy Abd-elkader, et al.
Publicado: (2022)

Hydroxypropyl chitosan nail lacquer of ciclopirox-PLGA nanocapsules for augmented in vitro nail plate absorption and onychomycosis treatment
por: Gaballah, Eman Yahya, et al.
Publicado: (2022)

IL-2 immunotherapy for targeting regulatory T cells in autoimmunity
por: Lykhopiy, Valentina, et al.
Publicado: (2023)

Natural killer cells and autoimmunity
por: French, Anthony R, et al.
Publicado: (2004)

The regulatory mechanism and potential application of IL-23 in autoimmune diseases
por: Xiong, De-Kai, et al.
Publicado: (2022)

Drug-Loaded Chitosan Scaffolds for Periodontal Tissue Regeneration
por: Atia, Gamal Abdel Nasser, et al.
Publicado: (2022)

Altered Regulatory B Cell Subsets in Children with Type 1 Diabetes Mellitus
por: El-Mokhtar, Mohamed A., et al.
Publicado: (2020)

Methotrexate conjugated gold nanoparticles improve rheumatoid vascular dysfunction in rat adjuvant-induced arthritis: gold revival
por: Rafik, Salma T., et al.
Publicado: (2022)

Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease
por: Lohr, Jens, et al.
Publicado: (2006)

Changes in natural killer cells and exhausted memory regulatory T Cells with corticosteroid therapy in acute autoimmune hepatitis
por: Jeffery, Hannah C., et al.
Publicado: (2018)

Role of IL-10-Producing Natural Killer Cells in the Regulatory Mechanisms of Inflammation during Systemic Infection
por: Martinez-Espinosa, Israel, et al.
Publicado: (2021)

Natural killer cells in human autoimmune disorders
por: Fogel, Leslie A, et al.
Publicado: (2013)

The Role of Natural Killer Cells in Autoimmune Diseases
por: Kucuksezer, Umut Can, et al.
Publicado: (2021)

Natural killer cells in inflammatory autoimmune diseases
por: Yang, Yuyan, et al.
Publicado: (2021)

Pioglitazone Synthetic Analogue Ameliorates Streptozotocin-Induced Diabetes Mellitus through Modulation of ACE 2/Angiotensin 1–7 via PI3K/AKT/mTOR Signaling Pathway
por: Ahmed, Yasmin M., et al.
Publicado: (2022)

IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease
por: Dambuza, Ivy M., et al.
Publicado: (2017)

The Cytotoxic Activity of Natural Killer Cells Is Suppressed by IL-10(+) Regulatory T Cells During Acute Retroviral Infection
por: Littwitz-Salomon, Elisabeth, et al.
Publicado: (2018)

Novel Clotrimazole and Vitis vinifera loaded chitosan nanoparticles: Antifungal and wound healing efficiencies
por: Elshaer, Esraa E., et al.
Publicado: (2022)

IL-10-producing regulatory B cells (B10 cells) in autoimmune disease
por: Kalampokis, Ioannis, et al.
Publicado: (2013)

Mechanisms of Regulatory B cell Function in Autoimmune and Inflammatory Diseases beyond IL-10
por: Ray, Avijit, et al.
Publicado: (2017)

Preparation of Lambda-Cyhalothrin-Loaded Chitosan Nanoparticles and Their Bioactivity against Drosophila suzukii
por: Shawer, Rady, et al.
Publicado: (2022)

The role of natural killer cells in pathogenesis of autoimmune diseases
por: Popko, Katarzyna, et al.
Publicado: (2016)

Therapeutic Potential of Invariant Natural Killer T Cells in Autoimmunity
por: Van Kaer, Luc, et al.
Publicado: (2018)

Editorial: The Role of Natural Killer Cells in Autoimmune Diseases
por: Fierabracci, Alessandra, et al.
Publicado: (2021)

Regulatory role of natural killer T cells in diabetes
por: Tard, Celine, et al.
Publicado: (2015)

Proximity-enabled covalent binding of IL-2 to IL-2Rα selectively activates regulatory T cells and suppresses autoimmunity
por: Zhang, Bo, et al.
Publicado: (2023)

IL-10 secreting regulatory B cells are potent arbiters of autoimmunity in both mouse and man
por: Mauri, Claudia, et al.
Publicado: (2011)

Modulation of autoimmune diseases by interleukin (IL)-17 producing regulatory T helper (Th17) cells
por: Singh, Bhagirath, et al.
Publicado: (2013)

Regulatory B Cells Control T Cell Autoimmunity Through IL-21-Dependent Cognate Interactions
por: Yoshizaki, Ayumi, et al.
Publicado: (2012)

Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity
por: Wang, Chun Jing, et al.
Publicado: (2022)

Cell type specific IL-27p28 (IL-30) deletion in mice uncovers an unexpected regulatory function of IL-30 in autoimmune inflammation
por: Kim, Dongkyun, et al.
Publicado: (2023)

Antifungal Carvacrol Loaded Chitosan Nanoparticles
por: Vitali, Alberto, et al.
Publicado: (2021)

Development of Apremilast Nanoemulsion-Loaded Chitosan Gels: In Vitro Evaluations and Anti-Inflammatory and Wound Healing Studies on a Rat Model
por: Ahmed, Mohammed Muqtader, et al.
Publicado: (2022)

Association of the polymorphisms of TRAF1 (rs10818488) and TNFAIP3 (rs2230926) with rheumatoid arthritis and systemic lupus erythematosus and their relationship to disease activity among Egyptian patients
por: Moaaz, Mai, et al.
Publicado: (2016)

Regulation of Experimental Autoimmune Encephalomyelitis by Natural Killer (NK) Cells
por: Zhang, Ben-ning, et al.
Publicado: (1997)

Liver Autoimmunity Triggered by Microbial Activation of Natural Killer T Cells
por: Mattner, Jochen, et al.
Publicado: (2008)

Therapeutic effect of melatonin-loaded chitosan/lecithin nanoparticles on hyperglycemia and pancreatic beta cells regeneration in streptozotocin-induced diabetic rats
por: Alaa, Habiba, et al.
Publicado: (2023)

Atorvastatin-loaded nanostructured lipid carriers (NLCs): strategy to overcome oral delivery drawbacks
por: Elmowafy, Mohammed, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_hroa7s41di3q85pga9jhp9qdac