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PGC-1α Signaling Increases GABA(A) Receptor Subunit α2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice

Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a master regulator of mitochondria biogenesis and cell stress playing a role in metabolic and degenerative diseases. In the brain PGC-1α expression has been localized mainly to GABAergic interneurons but its overall role is not...

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Detalles Bibliográficos
Autores principales: Vanaveski, Taavi, Molchanova, Svetlana, Pham, Dan Duc, Schäfer, Annika, Pajanoja, Ceren, Narvik, Jane, Srinivasan, Vignesh, Urb, Mari, Koivisto, Maria, Vasar, Eero, Timmusk, Tönis, Minkeviciene, Rimante, Eriksson, Ove, Lalowski, Maciej, Taira, Tomi, Korhonen, Laura, Voikar, Vootele, Lindholm, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882546/
https://www.ncbi.nlm.nih.gov/pubmed/33597848
http://dx.doi.org/10.3389/fnmol.2021.588230