Cargando…

PGC-1α Signaling Increases GABA(A) Receptor Subunit α2 Expression, GABAergic Neurotransmission and Anxiety-Like Behavior in Mice

Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a master regulator of mitochondria biogenesis and cell stress playing a role in metabolic and degenerative diseases. In the brain PGC-1α expression has been localized mainly to GABAergic interneurons but its overall role is not...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vanaveski, Taavi, Molchanova, Svetlana, Pham, Dan Duc, Schäfer, Annika, Pajanoja, Ceren, Narvik, Jane, Srinivasan, Vignesh, Urb, Mari, Koivisto, Maria, Vasar, Eero, Timmusk, Tönis, Minkeviciene, Rimante, Eriksson, Ove, Lalowski, Maciej, Taira, Tomi, Korhonen, Laura, Voikar, Vootele, Lindholm, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882546/ https://www.ncbi.nlm.nih.gov/pubmed/33597848 http://dx.doi.org/10.3389/fnmol.2021.588230

Ejemplares similares

Metabolic profile associated with distinct behavioral coping strategies of 129Sv and Bl6 mice in repeated motility test
por: Narvik, Jane, et al.
Publicado: (2018)

Repeated Administration of D-Amphetamine Induces Distinct Alterations in Behavior and Metabolite Levels in 129Sv and Bl6 Mouse Strains
por: Vanaveski, Taavi, et al.
Publicado: (2018)

Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells
por: Pham, Dan Duc, et al.
Publicado: (2019)

Promoter-Specific Expression and Genomic Structure of IgLON Family Genes in Mouse
por: Vanaveski, Taavi, et al.
Publicado: (2017)

Functional Diversity of Human Basic Helix-Loop-Helix Transcription Factor TCF4 Isoforms Generated by Alternative 5′ Exon Usage and Splicing
por: Sepp, Mari, et al.
Publicado: (2011)

Corticosterone induces DNA methyltransferases expression in rat cortical neurons
por: Urb, Mari, et al.
Publicado: (2015)

Distinctive behavioral and cellular responses to fluoxetine in the mouse model for Fragile X syndrome
por: Uutela, Marko, et al.
Publicado: (2014)

Repeated brief isoflurane anesthesia during early postnatal development produces negligible changes on adult behavior in male mice
por: Rosenholm, Marko, et al.
Publicado: (2017)

Housing mice in the individually ventilated or open cages—Does it matter for behavioral phenotype?
por: Åhlgren, Johanna, et al.
Publicado: (2019)

Three Pillars of Automated Home-Cage Phenotyping of Mice: Novel Findings, Refinement, and Reproducibility Based on Literature and Experience
por: Voikar, Vootele, et al.
Publicado: (2020)

The Unfolded Protein Response and Autophagy as Drug Targets in Neuropsychiatric Disorders
por: Srinivasan, Vignesh, et al.
Publicado: (2020)

Interneuronal GluK1 kainate receptors control maturation of GABAergic transmission and network synchrony in the hippocampus
por: Ojanen, Simo, et al.
Publicado: (2023)

Dynamic Interaction of USP14 with the Chaperone HSC70 Mediates Crosstalk between the Proteasome, ER Signaling, and Autophagy
por: Srinivasan, Vignesh, et al.
Publicado: (2019)

Neuronal-activity regulated gene expression: emphasis on BDNF
por: Timmusk, Tõnis
Publicado: (2015)

Short- and long-term habituation of auditory event-related potentials in the rat
por: Gurevicius, Kestutis, et al.
Publicado: (2014)

α(1)-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition
por: Perez, Dianne M.
Publicado: (2020)

Lsamp is implicated in the regulation of emotional and social behavior by use of alternative promoters in the brain
por: Philips, Mari-Anne, et al.
Publicado: (2014)

Evaluation of Social and Physical Enrichment in Modulation of Behavioural Phenotype in C57BL/6J Female Mice
por: Kulesskaya, Natalia, et al.
Publicado: (2011)

Commentary: LACTB is a tumour suppressor that modulates lipid metabolism and cell state
por: Eriksson, Ove, et al.
Publicado: (2017)

Multivariate analyses of immune markers reveal increases in plasma EN-RAGE in first-episode psychosis patients
por: Korhonen, Laura, et al.
Publicado: (2023)

Drastic Effects on the Microbiome of a Young Rower Engaged in High-Endurance Exercise After a Month Usage of a Dietary Fiber Supplement
por: Jaago, Mariliis, et al.
Publicado: (2021)

Unveiling the Function of the Mitochondrial Filament-Forming Protein LACTB in Lipid Metabolism and Cancer
por: Cascone, Annunziata, et al.
Publicado: (2022)

Role of Environment and Experimenter in Reproducibility of Behavioral Studies With Laboratory Mice
por: Nigri, Martina, et al.
Publicado: (2022)

Sphingolipids as Modulators of SARS-CoV-2 Infection
por: Törnquist, Kid, et al.
Publicado: (2021)

Effects of α-Synuclein Monomers Administration in the Gigantocellular Reticular Nucleus on Neurotransmission in Mouse Model
por: Joniec-Maciejak, Ilona, et al.
Publicado: (2019)

Alternative splicing and expression of human and mouse NFAT genes()
por: Vihma, Hanna, et al.
Publicado: (2008)

Expression analysis of the CLCA gene family in mouse and human with emphasis on the nervous system
por: Piirsoo, Marko, et al.
Publicado: (2009)

The role of carbonic anhydrase VI in bitter taste perception: evidence from the Car6(−/−) mouse model
por: Patrikainen, Maarit, et al.
Publicado: (2014)

Meta-coexpression conservation analysis of microarray data: a "subset" approach provides insight into brain-derived neurotrophic factor regulation
por: Aid-Pavlidis, Tamara, et al.
Publicado: (2009)

ADHD-like behaviors caused by inactivation of a transcription factor controlling the balance of inhibitory and excitatory neuron development in the mouse anterior brainstem
por: Morello, Francesca, et al.
Publicado: (2020)

Mixed housing with DBA/2 mice induces stress in C57BL/6 mice: implications for interventions based on social enrichment
por: Kulesskaya, Natalia, et al.
Publicado: (2014)

Two-fold elevation of endogenous GDNF levels in mice improves motor coordination without causing side-effects
por: Mätlik, Kärt, et al.
Publicado: (2018)

Female C57BL/6J Mice Show Alcohol-Seeking Behaviour after Withdrawal from Prolonged Alcohol Consumption in the Social Environment
por: Koskela, Maryna, et al.
Publicado: (2021)

Gas7 Is a Novel Dendritic Spine Initiation Factor
por: Khanal, Pushpa, et al.
Publicado: (2023)

Expression of NGF and GDNF family members and their receptors during peripheral nerve development and differentiation of Schwann cells in vitro
por: Piirsoo, Marko, et al.
Publicado: (2010)

Introducing Pitt-Hopkins syndrome-associated mutations of TCF4 to Drosophila daughterless
por: Tamberg, Laura, et al.
Publicado: (2015)

Novel transcripts reveal a complex structure of the human TRKA gene and imply the presence of multiple protein isoforms
por: Luberg, Kristi, et al.
Publicado: (2015)

The Importance of α-Klotho in Depression and Cognitive Impairment and Its Connection to Glutamate Neurotransmission—An Up-to-Date Review
por: Pańczyszyn-Trzewik, Patrycja, et al.
Publicado: (2023)

The ubiquitin proteasome system in synaptic and axonal degeneration: a new twist to an old cycle
por: Korhonen, Laura, et al.
Publicado: (2004)

Differential patterns of cross-reactive antibody response against SARS-CoV-2 spike protein detected for chronically ill and healthy COVID-19 naïve individuals
por: Jaago, Mariliis, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_i1sm9a8cs45pda1c0n1g50iuf9