Developmental malformations in Huntington disease: neuropathologic evidence of focal neuronal migration defects in a subset of adult brains

Neuropathologic hallmarks of Huntington Disease (HD) include the progressive neurodegeneration of the striatum and the presence of Huntingtin (HTT) aggregates that result from abnormal polyQ expansion of the HTT gene. Whether the pathogenic trinucleotide repeat expansion of the HTT gene causes neuro...

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Detalles Bibliográficos
Autores principales: Hickman, R. A., Faust, P. L., Rosenblum, M. K., Marder, K., Mehler, M. F., Vonsattel, J. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882590/
https://www.ncbi.nlm.nih.gov/pubmed/33517535
http://dx.doi.org/10.1007/s00401-021-02269-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882590/
https://www.ncbi.nlm.nih.gov/pubmed/33517535
http://dx.doi.org/10.1007/s00401-021-02269-4

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