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CD8(+)CD161(+) T-Cells: Cytotoxic Memory Cells With High Therapeutic Potential

NK1.1 and its human homolog CD161 are expressed on NK cells, subsets of CD4(+) and CD8(+) T cells, and NKT cells. While the expression of NK1.1 is thought to be inhibitory to NK cell function, it is reported to play both costimulatory and coinhibitory roles in T-cells. CD161 has been extensively stu...

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Detalles Bibliográficos
Autores principales: Konduri, Vanaja, Oyewole-Said, Damilola, Vazquez-Perez, Jonathan, Weldon, Scott A., Halpert, Matthew M., Levitt, Jonathan M., Decker, William K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882609/
https://www.ncbi.nlm.nih.gov/pubmed/33597948
http://dx.doi.org/10.3389/fimmu.2020.613204