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Interleukin-33 Amplifies Human Mast Cell Activities Induced by Complement Anaphylatoxins

Both, aberrant mast cell responses and complement activation contribute to allergic diseases. Since mast cells are highly responsive to C3a and C5a, while Interleukin-33 (IL-33) is a potent mast cell activator, we hypothesized that IL-33 critically regulates mast cell responses to complement anaphyl...

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Detalles Bibliográficos
Autores principales: West, Peter W., Bahri, Rajia, Garcia-Rodriguez, Karen M., Sweetland, Georgia, Wileman, Georgia, Shah, Rajesh, Montero, Angeles, Rapley, Laura, Bulfone-Paus, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882629/
https://www.ncbi.nlm.nih.gov/pubmed/33597949
http://dx.doi.org/10.3389/fimmu.2020.615236