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Cell Surface Expression of Endosomal Toll-Like Receptors—A Necessity or a Superfluous Duplication?

Timely and precise delivery of the endosomal Toll-like receptors (TLRs) to the ligand recognition site is a critical event in mounting an effective antimicrobial immune response, however, the same TLRs should maintain the delicate balance of avoiding recognition of self-nucleic acids. Such sensing i...

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Detalles Bibliográficos
Autores principales: Mielcarska, Matylda Barbara, Bossowska-Nowicka, Magdalena, Toka, Felix Ngosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882679/
https://www.ncbi.nlm.nih.gov/pubmed/33597952
http://dx.doi.org/10.3389/fimmu.2020.620972