Potentiating the Antitumor Activity of Cytotoxic T Cells via the Transmembrane Domain of IGSF4 That Increases TCR Avidity

A robust T-cell response is an important component of sustained antitumor immunity. In this respect, the avidity of TCR in the antigen-targeting of tumors is crucial for the quality of the T-cell response. This study reports that the transmembrane (TM) domain of immunoglobulin superfamily member 4 (...

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Detalles Bibliográficos
Autores principales: Kim, Hye-Ran, Park, Jeong-Su, Fatima, Yasmin, Kausar, Maiza, Park, Jin-Hwa, Jun, Chang-Duk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882689/
https://www.ncbi.nlm.nih.gov/pubmed/33597944
http://dx.doi.org/10.3389/fimmu.2020.591054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882689/
https://www.ncbi.nlm.nih.gov/pubmed/33597944
http://dx.doi.org/10.3389/fimmu.2020.591054

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