Systemic Inflammation Increases the Susceptibility to Levodopa-Induced Dyskinesia in 6-OHDA Lesioned Rats by Targeting the NR2B-Medicated PKC/MEK/ERK Pathway

Background: The long-term administration of levodopa (L-dopa), the gold-standard treatment for Parkinson's disease (PD), is irreparably associated with L-dopa-induced dyskinesia (LID), which dramatically affects the quality of life of patients. However, the underlying molecular mechanisms of ho...

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Detalles Bibliográficos
Autores principales: Yan, Aijuan, Song, Lu, Zhang, Yu, Wang, Xijin, Liu, Zhenguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882708/
https://www.ncbi.nlm.nih.gov/pubmed/33597857
http://dx.doi.org/10.3389/fnagi.2020.625166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882708/
https://www.ncbi.nlm.nih.gov/pubmed/33597857
http://dx.doi.org/10.3389/fnagi.2020.625166

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