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Metformin alleviates allergic airway inflammation and increases Treg cells in obese asthma

Obesity increases the morbidity and severity of asthma, with poor sensitivity to corticosteroid treatment. Metformin has potential effects on improving asthma airway inflammation. Regulatory T cells (Tregs) play a key role in suppressing the immunoreaction to allergens. We built an obese asthmatic m...

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Detalles Bibliográficos
Autores principales: Guo, Yimin, Shi, Jianting, Wang, Qiujie, Hong, Luna, Chen, Ming, Liu, Shanying, Yuan, Xiaoqing, Jiang, Shanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882927/
https://www.ncbi.nlm.nih.gov/pubmed/33421348
http://dx.doi.org/10.1111/jcmm.16269