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Neferine suppresses autophagy‐induced inflammation, oxidative stress and adipocyte differentiation in Graves' orbitopathy

Previous studies in Graves’ orbitopathy (GO) patient‐derived fibroblasts showed that inhibition of autophagy suppresses adipogenic differentiation. Autophagy activation is associated with inflammation, production of reactive oxygen species and fibrosis. Neferine is an alkaloid extracted from Nelumbo...

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Detalles Bibliográficos
Autores principales: Li, Hong, Gao, Long, Min, Jie, Yang, Yucheng, Zhang, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882929/
https://www.ncbi.nlm.nih.gov/pubmed/33443817
http://dx.doi.org/10.1111/jcmm.15931