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miR‐34a in extracellular vesicles from bone marrow mesenchymal stem cells reduces rheumatoid arthritis inflammation via the cyclin I/ATM/ATR/p53 axis

Extracellular vesicles (Evs) participate in the development of rheumatoid arthritis (RA), but the mechanisms remain unclear. This study aimed to determine the mechanism by which microRNA‐34a (miR‐34a) contained in bone marrow mesenchymal stem cell (BM‐MSC)‐derived Evs functions in RA fibroblast‐like...

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Detalles Bibliográficos
Autores principales: Wu, Huaiguo, Zhou, Xike, Wang, Xuedong, Cheng, Wei, Hu, Xinjia, Wang, Yueping, Luo, Bing, Huang, Wenjun, Gu, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882978/
https://www.ncbi.nlm.nih.gov/pubmed/33465281
http://dx.doi.org/10.1111/jcmm.15857