KLF4 down‐regulation resulting from TLR4 promotion of ERK1/2 phosphorylation underpins inflammatory response in sepsis

Sepsis is a systemic inflammatory response to invading pathogens, leading to high mortality rates in intensive care units worldwide. Krüppel‐like factor 4 (KLF4) is an important anti‐inflammatory transcription factor. In this study, we investigate the anti‐inflammatory role of KLF4 in caecal ligatio...

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Detalles Bibliográficos
Autores principales: Li, Chunwen, Yu, Lei, Mai, Chao, Mu, Tianyi, Zeng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882990/
https://www.ncbi.nlm.nih.gov/pubmed/33369167
http://dx.doi.org/10.1111/jcmm.16082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7882990/
https://www.ncbi.nlm.nih.gov/pubmed/33369167
http://dx.doi.org/10.1111/jcmm.16082

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