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Carveol a Naturally-Derived Potent and Emerging Nrf2 Activator Protects Against Acetaminophen-Induced Hepatotoxicity

Acetaminophen (N-acetyl p-aminophenol or APAP) is used worldwide for its antipyretic and anti-inflammatory potential. However, APAP overdose sometimes causes severe liver damage. In this study, we elucidated the protective effects of carveol in liver injury, using molecular and in silico approaches....

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Detalles Bibliográficos
Autores principales: Rahman, Zaif Ur, Al Kury, Lina Tariq, Alattar, Abdullah, Tan, Zhen, Alshaman, Reem, Malik, Imran, Badshah, Haroon, Uddin, Zia, Khan Khalil, Atif Ali, Muhammad, Naveed, Khan, Saifullah, Ali, Amjad, Shah, Fawad Ali, Li, Jing Bo, Li, Shupeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883019/
https://www.ncbi.nlm.nih.gov/pubmed/33597885
http://dx.doi.org/10.3389/fphar.2020.621538