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Steroid‐dependent switch of OvoL/Shavenbaby controls self‐renewal versus differentiation of intestinal stem cells

Adult stem cells must continuously fine‐tune their behavior to regenerate damaged organs and avoid tumors. While several signaling pathways are well known to regulate somatic stem cells, the underlying mechanisms remain largely unexplored. Here, we demonstrate a cell‐intrinsic role for the OvoL fami...

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Detalles Bibliográficos
Autores principales: Al Hayek, Sandy, Alsawadi, Ahmad, Kambris, Zakaria, Boquete, Jean‐Philippe, Bohère, Jérôme, Immarigeon, Clément, Ronsin, Brice, Plaza, Serge, Lemaitre, Bruno, Payre, François, Osman, Dani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883054/
https://www.ncbi.nlm.nih.gov/pubmed/33372708
http://dx.doi.org/10.15252/embj.2019104347