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Reverse fountain flow of phosphatidylinositol‐3,4‐bisphosphate polarizes migrating cells

The ability of cells to polarize and move toward external stimuli plays a crucial role in development, as well as in normal and pathological physiology. Migrating cells maintain dynamic complementary distributions of Ras activity and of the phospholipid phosphatidylinositol‐3,4‐bisphosphate (PI(3,4)...

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Detalles Bibliográficos
Autores principales: Li, Xiaoguang, Pal, Dhiman Sankar, Biswas, Debojyoti, Iglesias, Pablo A, Devreotes, Peter N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883298/
https://www.ncbi.nlm.nih.gov/pubmed/33586225
http://dx.doi.org/10.15252/embj.2020105094