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CCR5 signaling promotes lipopolysaccharide-induced macrophage recruitment and alveolar developmental arrest

The pathogenesis of bronchopulmonary dysplasia (BPD), involves inflammatory, mechanisms that are not fully characterized. Here we report that overexpression of C-C chemokine receptor 5 (CCR5) and its ligands is associated with BPD development. Lipopolysaccharide-induced BPD rats have increased CCR5...

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Detalles Bibliográficos
Autores principales: Chen, Ze, Xie, Xiaohua, Jiang, Na, Li, Jianhui, Shen, Lei, Zhang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883330/
https://www.ncbi.nlm.nih.gov/pubmed/33589608
http://dx.doi.org/10.1038/s41419-021-03464-7