Anti-Warburg effect by targeting HRD1-PFKP pathway may inhibit breast cancer progression

BACKGROUND: Our previous studies have shown that the E3 ubiquitin ligase of HMG-CoA reductase degradation 1 (HRD1) functions as a tumor suppressor, as overexpression of HRD1 suppressed breast cancer proliferation and invasion. However, its role in breast cancer cell glucose metabolism was unclear. H...

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Detalles Bibliográficos
Autores principales: Fan, Ya, Wang, Jia, Xu, Yuemei, Wang, Yipin, Song, Tao, Liang, Xiubin, Jin, Feng, Su, Dongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883444/
https://www.ncbi.nlm.nih.gov/pubmed/33588886
http://dx.doi.org/10.1186/s12964-020-00679-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883444/
https://www.ncbi.nlm.nih.gov/pubmed/33588886
http://dx.doi.org/10.1186/s12964-020-00679-7

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