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Anti-Warburg effect by targeting HRD1-PFKP pathway may inhibit breast cancer progression
BACKGROUND: Our previous studies have shown that the E3 ubiquitin ligase of HMG-CoA reductase degradation 1 (HRD1) functions as a tumor suppressor, as overexpression of HRD1 suppressed breast cancer proliferation and invasion. However, its role in breast cancer cell glucose metabolism was unclear. H...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883444/ https://www.ncbi.nlm.nih.gov/pubmed/33588886 http://dx.doi.org/10.1186/s12964-020-00679-7 |