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ATP-evoked intracellular Ca(2+) transients shape the ionic permeability of human microglia from epileptic temporal cortex
BACKGROUND: Intracellular Ca(2+) modulates several microglial activities, such as proliferation, migration, phagocytosis, and inflammatory mediator secretion. Extracellular ATP, the levels of which significantly change during epileptic seizures, activates specific receptors leading to an increase of...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883449/ https://www.ncbi.nlm.nih.gov/pubmed/33588880 http://dx.doi.org/10.1186/s12974-021-02096-0 |