Cargando…

CellWalker integrates single-cell and bulk data to resolve regulatory elements across cell types in complex tissues

Single-cell and bulk genomics assays have complementary strengths and weaknesses, and alone neither strategy can fully capture regulatory elements across the diversity of cells in complex tissues. We present CellWalker, a method that integrates single-cell open chromatin (scATAC-seq) data with gene...

Descripción completa

Detalles Bibliográficos
Autores principales: Przytycki, Pawel F., Pollard, Katherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883575/
https://www.ncbi.nlm.nih.gov/pubmed/33583425
http://dx.doi.org/10.1186/s13059-021-02279-1