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CellWalker integrates single-cell and bulk data to resolve regulatory elements across cell types in complex tissues
Single-cell and bulk genomics assays have complementary strengths and weaknesses, and alone neither strategy can fully capture regulatory elements across the diversity of cells in complex tissues. We present CellWalker, a method that integrates single-cell open chromatin (scATAC-seq) data with gene...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883575/ https://www.ncbi.nlm.nih.gov/pubmed/33583425 http://dx.doi.org/10.1186/s13059-021-02279-1 |