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SIRT1 and SIRT2 Activity Control in Neurodegenerative Diseases
Sirtuins are NAD(+) dependent histone deacetylases (HDAC) that play a pivotal role in neuroprotection and cellular senescence. SIRT1-7 are different homologs from sirtuins. They play a prominent role in many aspects of physiology and regulate crucial proteins. Modulation of sirtuins can thus be util...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883599/ https://www.ncbi.nlm.nih.gov/pubmed/33597872 http://dx.doi.org/10.3389/fphar.2020.585821 |