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SIRT1 and SIRT2 Activity Control in Neurodegenerative Diseases

Sirtuins are NAD(+) dependent histone deacetylases (HDAC) that play a pivotal role in neuroprotection and cellular senescence. SIRT1-7 are different homologs from sirtuins. They play a prominent role in many aspects of physiology and regulate crucial proteins. Modulation of sirtuins can thus be util...

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Detalles Bibliográficos
Autores principales: Manjula, Ramu, Anuja, Kumari, Alcain, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883599/
https://www.ncbi.nlm.nih.gov/pubmed/33597872
http://dx.doi.org/10.3389/fphar.2020.585821