Clinical trials optimizing investigator and self‐collection of buccal cells for RNA yield

OBJECTIVE: Buccal cells are an ideal surrogate tissue for studying biologic effects of carcinogens or drugs, however inherent fragility and salivary RNAses limit RNA yield. We conducted healthy volunteer trials to optimize collection conditions. METHODS: We conducted: (a) a single‐arm crossover stud...

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Detalles Bibliográficos
Autores principales: Geiger, Jessica L., Cedars, Elizabeth D., Zang, Yan, Normolle, Daniel P., Li, Hua, Grandis, Jennifer R., Centuori, Sara, Johnson, Daniel E., Bauman, Julie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Head and Neck, and Tumor Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883625/
https://www.ncbi.nlm.nih.gov/pubmed/33614939
http://dx.doi.org/10.1002/lio2.516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7883625/
https://www.ncbi.nlm.nih.gov/pubmed/33614939
http://dx.doi.org/10.1002/lio2.516

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